Generation of Open Metatarsal Fracture in Rats: A Model for Secondary Fracture Healing
نویسندگان
چکیده
منابع مشابه
Mandibular Fracture Healing in Rats
Purpose: To establish a rat mandibular fracture model and investigate the shortand long-term effects of recombinant parathyroid hormone (PTH 1-34) on mandibular fracture healing in rats. Materials and Methods: A controlled unilateral mandibular fracture was created surgically in 29 male Sprague-Dawley rats and then stabilized using an external fixation device. The rats were divided into 2 group...
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Bone fractures are one of the leading causes of emergency room visits worldwide, with approximately 8 million bony fractures occurring annually in the US alone. Although the majority of fractures do not cause significant long-term morbidity and mortality, approximately 10% of these fractures result in impaired fracture healing, drastically affecting quality of life in affected patients. By incr...
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Osteoporosis is determined by decreased bone strength that increases the threat of fractures. The aim of this study was to evaluate the effects of pentoxifylline (PTX) and alendronate (ALN), on the stereological parameters, and gene expression in callus of fracture in an experimental rat model of ovariectomy-induced osteoporosis (OVX). The OVX was induced in 90 female rats. Fourteen weeks later...
متن کاملFracture healing
Those of us who have experienced a significant fracture likely recall first the pain of the injury, then we often focus our attention on the prospect of time in a cast or other form of extended immobilization. We imagine the discomfort and limitations that will ensue, and after all else settles down, we often wonder, “How strong are my bones anyway, and will I fracture again?” Nature, on the o...
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ژورنال
عنوان ژورنال: SciMedicine Journal
سال: 2020
ISSN: 2704-9833
DOI: 10.28991/scimedj-2020-0204-2